Peripheral Blood

Peripheral Blood

Peripheral Blood

Peripheral Blood

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Peripheral Blood

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MORE INFORMATION

Common Questions

What is pharmacogenomics (PGx)?

Pharmacogenomics is the study of genetic variations that influence an individual’s response to medications. Each person responds uniquely to treatment so the same approach may not be effective or may cause adverse side effects in other patients. Understanding this information is helpful to physicians in developing a strategy to optimize medicine therapies. Data with respect to a patient’s genotype is used to maximize medicine efficacy while minimizing adverse drug effects and drug-drug interactions.

In Short, Pharmacogenomic (PGx) testing saves lives, by helping physicians prescribe the right medication for a patient taking the guesswork and the trial & error out of prescribing and decreasing the time to proper treatment.

The PGx Test can be useful for understanding the impact of the medications that are being used today but can also help for future treatments. This is because many commonly prescribed medicine are impacted by a handful of genes so there will be overlap for results and it is highly likely that the result of one PGx test will be useful for future treatments. Because a PGx test result can help to inform other treatment decisions in the future for a patient’s care, results should be shared with other providers and potentially even the patient’s pharmacist.

A single test designed to inform treatment decisions:

✔ Patients demonstrating sensitivity or lack of symptom relief.

✔ Patients with chronic conditions and multiple prescriptions.

✔ Patients with a history of poor compliance.

✔ Patients with pharmacotherapy failure.

✔ Patients with a personal or family history of adverse medical reactions in response to certain medications.

Adverse Drug Reactions

Adverse drug reactions are a leading cause of death nationwide. The FDA highlights pharmacogenomics data for more than 130 prescription medications indicating their strong support for testing.

Pharmacogenomic (PGx) Testing provides evidence-based, actionable data for clinicians. This will help predict if a patient is likely to experience an adverse drug reaction or not respond to a given medicine at all.

The level of medicine interactions is reported with warnings, level of documentation, and clinical management recommendations.

Why does some medicine work for some people while not for others? Everyone’s metabolism is different.

What type of results can you expect?

Why do drugs work for some people while not for others? Everyone’s metabolism is different.

  • Extensive (normal) Metabolizer
  • Intermediate Metabolizer
  • Poor Metabolizer
  • Ultra-rapid Metabolizer
Based on genetics, everyone has the potential to respond to medication differently:
  • Medication is ineffective
  • Patient experiences unexpected reaction
  • Serious side effect occurs
  • A higher dosage is needed
  • A lower dosage is needed
Why play trial and error with your medication when you can know for sure?
Common Medications Affected

Results are available to you in 7-14 days. Why wait to see if a medication will work when you can know for sure?

Common medications affected by drug/gene and drug/drug interactions where patients should be genetically tested for:

Abacavir Ado-Trastuzumab Emtansine Afatinib
Amitriptyline Anastrozole Aripiprazole
Arsenic Trioxide Atomoxetine Azathioprine
Boceprevir Bosutinib Busulfan
Capecitabine Carbamazepine Carglumic Acid
Carisoprodol Carvedilol Calecoxib
Cetuximab Cevimeline Chloroquine
Chlorpropamide Cisplatin Citalopram
Clobazam Clomipramine Clopidogrel
Clozapine Codeine Crizotinib
Dabrafenib Dapsone Dasatinib
Denileukin Diftitox Desipramin Dexlansoprazole
Dextromethorphan and Quinidine Dizaepam Doxepin
Drospirenone and Ethinyl Estradiol Eltrombopag Erlotinib
Esomeprazole Everolimus Exemestane
Flurouracil Fluoxetine Flurbiprofen
Fluvoxamine Fulvestrant Galantamine
Glimepiride Glipizide Glyburide
Ibritumomab Tiuxetan Iloperidone Imatinib
Imipramine Indacaterol Irinotecan
Isosorbide and Hydralazine Ivacaftor Lansoprazole
Lapatinib Lenalidomide Letrozole
Lomitapide Mafenide Maraviroc
Mercaptopurine Methylene Blue Metoclopramide
Metoprolol Mipomersen Modafinil
Mycophenolic Acid Nalidixic Acid Nefazodone
Nilotinib Nitrofurantoin Nortriptyline
Obinutuzumab Ofatumumab Omacetaxine
Omeprazole Panitumumab Pantoprazole
Paroxetine Pazopanib PEG-3350
Peginterferon alfa-2b Pegloticase Perphenazine
Petuzumab Phenytoin Pimozide
Ponatinib Prasugrel Pravastatin
Primaquin Propafenone Propranolol
Protriptyline Quinidine Quinine Sulfate
Rabeprazole Rasburicase Rifampin
Risperidone Rituximab Rsuvastatin
Simeprevir Sodium Nitrate Sofosbuvir
Succimer Sulfamethoxazole Tamoxifen
Telaprevir Terbinafine Tetrabenazine
Thioguanine Thioridazine Ticagrelor
Tolterodine Tositumomab Tramadol
Trametinib Trastuzumab Tretinoin
Trimipramine Valproic Acid Vemurafenib
Venlafaxine Voriconazole Vortioxetine
Warfarin
What is pharmacogenomics (PGx)?

In short, pharmacogenomic (PGx) testing saves lives, by helping physicians prescribe the right medication for a patient by taking the trial & error out of prescribing and thus decreasing the time it would take to receive proper treatment.

Many patients have experienced the feeling that they cannot tolerate a medication or may feel that it is not helping them. This can cause a patient to have to return to their doctor over and over to try to find a medication that works better for them or has fewer side effects. The PGx test will scientifically determine how your body will metabolize different medications. The doctor can then prescribe a more effective and safer medication from the first appointment.

PGx Test can be useful for understanding the impact of the medications that are being used today but can also help for future treatments. This is because many commonly prescribed medicines are impacted by a handful of genes so there will be overlap for results and it is highly likely that the result of one PGx test will be useful for future treatments.

Thus, the PGx test results are not only important for the medication which prompted the testing but potentially for other medicines prescribed in the future. Because a PGx test result can help inform other treatment decisions in the future for a patient’s care, results should be shared with other providers and potentially even the patient’s pharmacist.

Who benefits from PGx testing?
  • Patients that experience less than optimal results from prescribed medications.
  • Patients with a personal or family history of adverse drug reactions in response to certain medications.
  • Patients taking multiple prescription medications for multiple chronic conditions.

Adverse drug reactions are a leading cause of death nationwide. The FDA highlights pharmacogenomics data for more than 130 prescription medications indicating their strong support for testing. Pharmacogenomic (PGx) Testing provides evidence-based, actionable data for clinicians. This will help predict if a patient is likely to experience an adverse medicine reaction or not respond to a given medicine at all.

What can you expect for results from PGx testing?

Why do drugs work for some people while not for others? Everyone’s metabolism is different.

  • Extensive (normal) Metabolizer
  • Intermediate Metabolizer
  • Poor Metabolizer
  • Ultra-rapid Metabolizer
Based on genetics, everyone has the potential to respond to medication differently:
  • Medication is ineffective
  • Patient experiences unexpected reaction
  • Serious side effect occurs
  • A higher dosage is needed
  • A lower dosage is needed
Why play trial and error with your medication when you can know for sure?

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Tesis Biosciences

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Scottsdale, AZ 85258

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