CGx Testing

CGx testing is a preventative gene test that looks for specific inherited changes (mutations) in a person’s genetic make-up. Harmful mutations may increase a persons’ chance, or risk, of developing a disease such as cancer. These conditions are considered hereditary. Appropriate genetic testing may be used to determine an individual’s risk and potential treatment options as indicated. Genetic mutations can have harmful, beneficial, neutral (no effect), or uncertain effects on health. Harmful mutations may increase a person’s chance, or risk, of developing a disease such as cancer. Overall, inherited mutations are thought to play a role in about 5 to 10 percent of all cancers.

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CGx Testing

CGx Testing is a preventative gene test that looks for specific inherited changes (mutations) in a person’s genetic make-up. Harmful mutations may increase a persons’ chance, or risk, of developing a disease such as cancer. These conditions are considered hereditary. Appropriate genetic testing may be used to determine an individual’s risk and potential treatment options as indicated. Some people inherit mutation(s) in the germline, allowing for the mutations to be passed on from parents to their children just like our harmless genetic traits such as height or eye color.

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Which patients qualify for testing?

Patients with several first-degree relatives (mother, father, sisters, brothers, children) with cancer or a history of cancer.
Patients that have many relatives on one side of the family who have had the same type of cancer.
Patients that have a family member with more than one type of cancer (like a woman with breast and ovarian).
Patients that have family members who had cancer at a younger age than normal for that type of cancer (Like colon cancer in a 20-year-old female).
Patients with an ethnicity (for example, Ashkenazi Jewish ancestry) that is linked to ovarian and breast cancers.

Patients that have a cluster of cancers in your family that are known to be linked to a single gene mutation (such as breast, ovarian, and pancreatic cancers in your family).
Patients that have had cancer in the past.
Patients with family members that have cancers occurring in both of a pair of organs (like both eyes, both kidneys, or both breasts).
Patients that have family members with more than one childhood cancer in siblings (like sarcoma in both a brother and a sister).
Patients that have family members that have cancer occurring in the sex that is usually not affected (like breast cancer in a man).

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